Antoine Tarquin Huet

This paper introduces ChReef, an improved optogenetic tool with enhanced performance in sensory and cardiac systems, demonstrating its effectiveness in restoring visual and auditory function.

This study improves optogenetic modification of spiral ganglion neurons in gerbils using microcatheter-based AAV delivery, achieving reliable ChR expression in 80% of treated animals but with limited transduction efficiency.

This paper develops a framework for optogenetic control of the auditory pathway by optimizing light pulse parameters to enhance spike probability and information encoding in spiral ganglion neurons.

The paper develops fast photoswitchable ligands for controlling neuronal activity in the cochlea, enabling rapid and sustained photocontrol without genetic modification.

The paper uses PSTR to predict adaptation and spontaneous firing rates in human auditory nerve fibers, showing agreement with single-unit recordings in animals.