Author

E Sitarska

Boston Children's HospitalORCID 0000-0001-6910-0876Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Anand SaminathaniD· 2 shared Elliott SomervilleiD· 2 shared Gustavo ScanavachiiD· 2 shared Tomas L. KirchhauseniD· 2 shared Anwesha SanyaliD· 1 shared Athanasios OikonomouiD· 1 shared Athul NairiD· 1 shared Beren AylaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Anand SaminathanORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 2, 2026

Naked antisense oligonucleotides access the cytosol during early endocytic trafficking

E Sitarska, Anand Saminathan, Gustavo Scanavachi…·Tomas L. Kirchhausen

This study tracks antisense oligonucleotides (ASOs) through endocytic trafficking, finding that productive escape occurs early in endosomes before sequestration in late compartments.

1 citation

humanexperimental assay

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Cell BiologyThe Journal of Cell BiologyPeer-reviewedNov 15, 2024

Constitutive Endolysosomal Perforation in Neurons allows Induction of alpha-Synuclein Aggregation by Internalized Pre-Formed Fibrils

Anwesha Sanyal, Gustavo Scanavachi, Elliott Somerville…·Tomas L. Kirchhausen

The paper shows that neurons have constitutive endolysosomal perforations enabling internalized alpha-synuclein fibrils to induce aggregation, and inhibiting PIKfyve kinase reduces this effect.

27 citationstop 2%

humanmouse

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