Author

Mirela Kuka

Vita-Salute San Raffaele UniversityORCID 0000-0001-9418-1559Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Eleonora SalaiD· 2 shared Marta MangioneiD· 2 shared Matteo IannaconeiD· 2 shared Alberto Bigogno· 1 shared Amir GiladiiD· 1 shared Burkhard BecheriD· 1 shared Carina B. Nava LausoniD· 1 shared Carlotta CatozziiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Eleonora SalaORCID

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2 papers

Recent·Most cited

ImmunologyThe EMBO JournalPeer-reviewedApr 1, 2025

T cell-derived IFN-γ Suppresses T Follicular Helper Cell Differentiation and Antibody Responses

Eleonora Sala, Maria Nelli, Chiara Laura…·Mirela Kuka

The paper shows that T cell-derived IFN-γ suppresses TFH differentiation and antibody responses by acting through dendritic cells, not directly on CD4+ T cells.

6 citations

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologyNature CommunicationsPeer-reviewedAug 27, 2024

LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness.

Isabella Pallavicini, Teresa Maria Frasconi, Carlotta Catozzi…·Teresa Manzo

This study shows that inhibiting LSD1 enhances CD8+ T cell function in adoptive T cell therapy, leading to improved antitumor immunity and synergistic effects with anti-PDL1 therapy.

22 citations

mouseCITE-seq

𝕏 PostBluesky