ImmunologyNature CommunicationsPeer-reviewed
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness
Xingxing Zhu, Yue Wu, Yanfeng Li…·Hu Zeng
This study shows that Rag-GTPases regulate B cell metabolism and immunity by restraining TFEB/TFE3 to maintain mitochondrial fitness and support T-independent humoral immunity.
12 citations