Ariel L. Raybuck

The paper shows that glutaminolysis and mitochondrial metabolism are conditionally crucial for B cell differentiation and cytokine signaling, revealing metabolic regulation of plasma cell generation and cytokine receptor signaling.

This study shows that Rag-GTPases regulate B cell metabolism and immunity by restraining TFEB/TFE3 to maintain mitochondrial fitness and support T-independent humoral immunity.

This study shows that glucose influx is critical for germinal center function and plasma cell production, but plasma cells can also use alternative hexose sugars for antibody secretion.