David R. Martinez

This study develops a tetravalent dengue mRNA vaccine that induces broad, durable, and protective immunity across all four serotypes in mice.

The paper identifies endothelial protein C receptor (EPCR) as an entry receptor for Langya and related parahenipaviruses and describes the structural basis of this interaction.

This study shows that intranasal vaccination with a synthetic spike protein and adjuvants elicits durable mucosal IgA and protects against zoonotic SARS-like coronaviruses.

This study designs epitope-focused immunogens targeting conserved coronavirus regions, showing broad neutralizing activity and protection in mice against diverse coronaviruses.

The paper identifies a broadly neutralizing antibody targeting the S2 subunit of sarbecoviruses, revealing a conserved site of vulnerability in the spike protein.

Non-stabilized SARS-CoV-2 Spike mRNA vaccination in macaques induces B cell lineages targeting conserved epitopes on Omicron variants or cross-neutralizing epitopes on Sarbecoviruses.

This study identifies bat and mink ACE2 as receptors for HKU5 merbecovirus, revealing distinct receptor interactions and highlighting mustelids as potential intermediate hosts.