Author

Angika Basant

The Francis Crick InstituteORCID 0000-0002-4754-6647Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Luyan CaoiD· 2 shared Michael WayiD· 2 shared Miroslav MladenoviD· 2 shared Antoine G. JegouiD· 1 shared Guillaume Romet‐LemonneiD· 1 shared Manos MavrakisiD· 1 shared Naoko KogataiD· 1 shared Shaina Chor Mei HuangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Luyan CaoORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 3, 2026

✦ In-depth digest

SPIN90 modulates the architecture of lamellipodial actin in an ARPC5L dependent fashion.

Luyan Cao, Angika Basant, Miroslav Mladenov…·Michael Way

SPIN90 selectively activates ArpC5L-containing Arp2/3 complexes to make linear actin filaments, shaping lamellipodial filament orientation and protrusion efficiency in B16 melanoma cells.

1 citation

humanmouse

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BiochemistryEMBO ReportsPeer-reviewedJul 15, 2024

CK-666 and CK-869 differentially inhibit Arp2/3 iso-complexes

Luyan Cao, Shaina Chor Mei Huang, Angika Basant…·Michael Way

This study shows CK-666 and CK-869 differentially inhibit Arp2/3 iso-complexes, with CK-869 uniquely affecting ArpC1B and Arp3-containing complexes, impacting phagocytosis and migration in macrophages.

27 citationstop 5%

mouseexperimental assay

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