Author
QB3ORCID 0000-0002-4822-4316Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Elias Adriaenssens, Stefan Schaar, Annan SI Cook…·Sascha Martens
Annan SI Cook, Minghao Chen, Thanh Ngoc Nguyen…·James H. Hurley
This study maps the structural pathway of class III PI 3-kinase activation by showing how N-myristoylation of VPS15 stabilizes the inactive conformation and how GTP binding promotes activation.
Kyle L. Morris, Cosmo Z. Buffalo, Christina Martina Stürzel…·James H. Hurley
The paper reveals how HIV-1 Nef modulates AP-1 trimerization through cargo dynamics and phosphorylation to regulate tetherin and MHC-I downregulation.