Jingjing Wang

This study identifies CLSTN3B as a driver of MASLD by promoting LD biogenesis and altering lipid partitioning between LDs and mitochondria, leading to mitochondrial dysfunction and oxidative stress.

This study shows that liver cancer initiation depends on metabolic zonation but is not linked to premalignant clonal expansion.

This study shows that CLSTN3B promotes lipid droplet maturation in hepatocytes and that its deletion reduces steatohepatitis in mice, with a positive correlation between CLSTN3B expression and MASLD severity in humans.

This study investigates how CIDEB loss-of-function mutations protect against fatty liver disease by enhancing β-oxidation through ATGL and PPARα activation.

Deepurify uses a multi-modal deep language model with contrastive learning to improve MAG decontamination by leveraging genomic sequences and taxonomic lineages.