Tom Dendooven

This study uses cryo-ET and cryo-EM to reveal the molecular architecture and spatial organisation of proteasomes in human sperm nuclei, identifying unique features and their role in proteolysis.

The paper determines the sub-nanometer structure of the SUN5-Nesprin3 LINC complex in human sperm cells, revealing its role in nuclear envelope remodelling and male infertility.

This study shows that dinoflagellates can acquire and utilize haptophyte-derived plastids, demonstrating that complex plastids can be transferred between hosts.

This study investigates the structural and functional changes in human sperm nuclear pore complexes (NPCs) during spermatogenesis, revealing a reduced central channel and altered transport dynamics.

DynaMight improves cryo-EM reconstruction by estimating molecular motions through 3D deformation learning and error estimation using VAEs.

The paper describes the structure of the budding yeast outer kinetochore complexes and how phosphorylation regulates their stability during mitotic error correction.

The paper describes how Hfq and Crc form mRNA-specific ribonucleoprotein assemblies that enable selective translational repression in Pseudomonas aeruginosa.

The paper identifies the stem loop 2 motif as a vulnerable site in SARS-CoV-2 that can be targeted by antisense oligonucleotides to inhibit replication and infection.