Author

Dylan Sosa

University of ChicagoORCID 0000-0003-3162-0643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:long-read sequencing· 1 Organism:plant (other)· 1

Frequent Co-Authors

Jianhai CheniD· 3 shared Manyuan LongiD· 3 shared Shengqian XiaiD· 3 shared Deanna ArsalaiD· 2 shared Alexander GuzzettaiD· 1 shared Bairong SheniD· 1 shared Dong WangiD· 1 shared Jared AtlasiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersEvolutionary Biology

Jianhai ChenORCID

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3 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintNov 24, 2025

Sex-biased duplicates are rapidly generated during Drosophila tRNA repertoire evolution

Dylan Sosa, Marek Sobczyk, Jianhai Chen…·Manyuan Long

The paper studies tRNA gene evolution in Drosophila, finding rapid duplication and loss, sexual dimorphism in expression, and implications for regulatory diversity.

DOI 10.1101/2025.11.24.689867

Drosophilalong-read sequencing

𝕏 PostBluesky

Evolutionary BiologyGenome Biology and EvolutionPeer-reviewedMay 16, 2024

One million years of solitude: the rapid evolution of de novo protein structure and complex

Jianhai Chen, Qingrong Li, Shengqian Xia…·Manyuan Long

This study examines the rapid structural evolution of de novo genes in rice over 1 million years, finding faster changes in disordered regions and structured elements compared to gene duplicates.

17 citations

plant (other)protein structure

𝕏 PostBluesky

Evolutionary BiologybioRxivNov 14, 2023

Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.

Jianhai Chen, Patrick Landback, Deanna Arsala…·Manyuan Long

This study identifies evolutionarily new genes in humans with disease phenotypes, showing their enrichment in male reproductive diseases and adaptive traits like brain size and color vision.

9 citations

humanstatistical model

𝕏 PostBluesky