Lucie E. Bourne

This study shows that TNAP and PHOSPHO1 are crucial for craniofacial and dental development, with their combined deletion causing severe hypoplasia and mineralisation defects.

This study shows that microarchitectural features of articular calcified cartilage in mice predict abnormal strain distributions in osteoarthritis.

This study investigates the synergistic roles of TNAP and PHOSPHO1 in postnatal bone mineralisation using a novel murine knockout model, revealing their critical function in biomineralisation and skeletal development.

This study uses imaging and modeling to show how structural changes in knee joints predict osteoarthritis onset by altering strain distribution.

This study investigates the sex-specific effects of prenatal alcohol exposure on the murine skeleton, finding divergent impacts on bone formation, trabecular structure, and cortical bone parameters between male and female mice.