Developmental BiologybioRxivPreprint
Craniofacial abnormalities from TNAP and PHOSPHO1 deletion highlight their dual role in bone and tooth mineralisation
Lucie E Bourne, Natalie Crump, Maya Karmali…·Katherine A Staines
This study shows that TNAP and PHOSPHO1 are crucial for craniofacial and dental development, with their combined deletion causing severe hypoplasia and mineralisation defects.
DOI 10.64898/2026.11.10.765640