Lucinda Evans

This study shows that TNAP and PHOSPHO1 are crucial for craniofacial and dental development, with their combined deletion causing severe hypoplasia and mineralisation defects.

This study investigates the synergistic roles of TNAP and PHOSPHO1 in postnatal bone mineralisation using a novel murine knockout model, revealing their critical function in biomineralisation and skeletal development.

This study investigates the regulation and function of trans-physeal growth plate bridges in mice, finding they serve a mechanical role to reduce epiphyseal shear stress during bone growth.

This study uses imaging and modeling to show how structural changes in knee joints predict osteoarthritis onset by altering strain distribution.

This study uses cryogenic X-ray phase-contrast imaging to analyze cartilage thickness and chondrocyte morphology in mouse joints, revealing differences between osteoarthritis-prone and healthy strains.