Mining folded proteomes in the era of accurate structure prediction
Charles Bayly-Jones, James C. Whisstock
The paper uses fold recognition algorithms to mine the AlphaFold structure database for novel protein family members and functional insights.
Author
Monash UniversityORCID 0000-0003-4200-5611Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Charles Bayly-Jones, James C. Whisstock
The paper uses fold recognition algorithms to mine the AlphaFold structure database for novel protein family members and functional insights.
Daniel Bakopoulos, James C. Whisstock, Coral G. Warr, Travis K. Johnson
This study identifies Pvf2 as a key regulator of macrophage self-renewal in Drosophila by showing its transient expression in blood cells and its role in driving population expansion.
Siew Siew Pang, Charles Bayly-Jones, Mazdak Radjainia…·James C. Whisstock
This paper determines the structure of MPEG-1, showing it forms a pre-pore complex and can perforate membranes under acidic conditions.
Michelle A. Henstridge, Lucinda C. Aulsebrook, Takashi Koyama…·Coral G. Warr
The paper identifies Torso-like as a secreted protein that regulates insulin signalling in Drosophila by modulating insulin-like peptide activity and developmental timing.