Giulia Maria Piperno

This study identifies the role of mature dendritic cells type 1 in forming, maintaining, and functioning tertiary lymphoid structures in cancer.

This study shows that WASp in macrophages prevents inflammation by maintaining nuclear integrity under mechanical stress, linking mechano-sensing to inflammatory responses.

The paper shows that ALCAM-mediated synapses between DC1 and CD8 T cells decrease in advanced lung tumors, impairing immune responses.

This study shows TIM4 enables large peritoneal macrophages to cross-present tumor antigens early in tumorigenesis, promoting CD8 T cell activation and immune surveillance.

The paper shows that DC-based therapy enhances CD8 T cell responses to neoantigens in lung tumors, particularly in high TMB tumors.

This study identifies a mitochondrial quality control mechanism that reverses phagosome maturation arrest caused by Mycobacterium tuberculosis through RAB7 recruitment and lysosomal targeting.