flow cytometry

The paper identifies GPR15+ CD38+ peripheral blood Th2 cells associated with active eosinophilic esophagitis, showing potential as a non-invasive biomarker and suggesting new disease mechanisms.

This study uses DNA origami calibrator beads to calibrate and compare the sensitivity of five flow cytometers for detecting dimly fluorescent nano-sized particles.

This study compares the effects of PRRSV-1 and swine influenza A virus on respiratory lymph node B cells and macrophages, identifying PRRSV-specific immune evasion mechanisms.

The paper shows that intrathymic HSPC transplantation restores T cell development via ILC3-TEC interactions in a ZAP-70-deficient mouse model.

The paper uses mass cytometry to analyze immune and signaling profiles in CML patients within hours of TKI treatment to predict 12-month treatment response.

The paper identifies T cell activation and PD-1/PD-L1 signaling as biomarkers for diabetic foot ulcer healing using multi-omics approaches across multiple cohorts.

The paper uses deep phenomics to compare immune cell activation in whole blood and PBMCs, finding neutrophils and NK cells as primary sources of CCL4 production in WB and PBMCs, respectively.

This study examines skin neuroimmune changes in fibromyalgia patients, identifying novel dermal alterations and correlations between immune cell populations and nerve fiber density.

The paper identifies specific T-cell subsets with gut-homing/residency markers that predict HIV status and subclinical atherosclerosis in ART-treated individuals.

The paper quantifies T cell response dynamics during primary SARS-CoV-2 infection, showing clone-intrinsic properties drive clonal kinetics and providing insights for vaccine design.

The paper identifies phospho-LCK (pY394) as a biomarker for dasatinib sensitivity in paediatric T-ALL using flow-cytometry, showing strong correlation with drug response.

The paper examines how B-cell subsets in ocrelizumab-treated multiple sclerosis patients influence vaccine responses to SARS-CoV-2, identifying specific B-cell populations associated with immune response variability.

The paper identifies a peptide that binds to cholangiocytes and uses it to isolate human and rat liver epithelial cells, revealing functional differences between small and large cholangiocytes.

This paper identifies Siglec-10/α3β1 integrin interactions as a mechanism suppressing macrophage phagocytosis in PDAC and shows that targeting these interactions enhances anti-tumor immunity.

The paper uses flow cytometry to identify and characterize hemocyte subsets in the American cockroach, finding that granular hemocytes perform key immune functions like phagocytosis and melanization.

This study compares the effects of cytomegalovirus and rheumatoid arthritis on senescent CD4+ T cells using mass cytometry, finding distinct differentiation and functional profiles.

This study shows that beta-2-microglobulin enhances neutrophil phagocytosis of bacteria and apoptotic cells, contributing to innate immunity and tissue homeostasis.

This study generates and matures bone marrow-derived dendritic cells in vitro using STING activation to enhance CD8 T cell priming.

The paper measures ligand discrimination errors and molecular noise in immune cells of ER+ breast cancer patients compared to healthy controls using a communication model.

This study shows that dietary iron deficiency impairs memory T cell function after influenza infection, specifically reducing IFN-gamma production without recovery through dendritic cell co-culture.

The paper develops a 37-color spectral flow cytometry panel to analyze T cell phenotypes and cytokine expression in human intestinal samples, with applications in inflammatory bowel disease research.

This study uses multi-omic profiling to analyze immune cell dynamics in healthy adults over time, finding age-related transcriptional changes in T cells and impaired memory B cell responses in older adults.

This study shows that acetoacetate suppresses colon cancer by expanding and activating MAIT cells via the MR1 receptor, offering a potential immunotherapy approach.

This study shows low-dose CD28-SA infusion reduces inflammation and promotes wound healing in pigs after myocardial infarction by increasing Treg cells and reducing TNF-producing cells.

AutoSpectral enhances spectral flow cytometry accuracy by optimizing unmixing matrices and matching autofluorescence at the cellular level, significantly reducing errors in complex datasets.

The study uses spectral flow cytometry to analyze immune function across populations, revealing geographical differences and TLR8's role in mRNA vaccine responses.

The paper shows that CCR2-driven monocyte recruitment reduces radiotherapy-induced intestinal toxicity by enhancing IL-17 production.

This study expands adaptive NKG2C+ NK cells from HBV-infected donors, showing enhanced ADCC and anti-hepatoma activity.

This study shows hemin induces HO-1 in macrophages, inhibiting STING pathway activation and promoting endometriosis development.