imaging

Born on Mars: Multigenerational phenotypic change in Caenorhabditis elegans under Martian analog gravity and hypomagnetic fields

This study examines transgenerational effects of Martian analog gravity and hypomagnetic fields on C. elegans, finding progressive impairments and increased phenotypic variability across generations.

Visualization and Morphological Analysis of Individual Oligodendrocytes in the Mouse White Matter

The paper describes methods to visualize and analyze the morphology of individual oligodendrocytes in mouse white matter using genetic labeling and immunostaining techniques.

Cartilage canals in sharks and rays show that blood vessels can exist in mature cartilage without triggering endochondral bone formation

This study shows that sharks and rays have cartilage canals in their adult skeletons, which are vascular but do not trigger endochondral bone formation, suggesting an ancient role in nutrient transport.

Extending digital biology: bacterial survival and morphological heterogeneity under antibiotic stress

This study develops a workflow to generate morphological signatures of bacterial progeny under antibiotic stress, revealing distinct morphologies linked to survival and antibiotic type.

Detecting Sleep Deprivation from Running Biomechanics Using Machine Learning Classification: A Comparison Between Wearable and Laboratory Motion Capture

This study compares wearable and lab motion capture systems in detecting sleep deprivation through running biomechanics using machine learning, finding both systems can identify individual biomechanical changes but fail between-subject classification without personalized data.

Eigenmode decomposition of asymmetries in whole-brain effective connectivity reveals multiscale hierarchical dynamics

This paper decomposes whole-brain effective connectivity to reveal multiscale hierarchical dynamics and their relation to temporal irreversibility and individual-specific signatures.

Neural mechanisms underlying the effects of cognitive fatigue on physical effort-based decision-making

This study shows that cognitive fatigue increases perceived costs of physical effort by altering brain signals in the dorsolateral prefrontal cortex and insula.

Nanoscale imaging resolves canonical topology and intracellular dynamics of SUN5/SPAG4L during mammalian spermiogenesis

This study uses advanced imaging techniques to clarify SUN5's localization and dynamics during spermiogenesis, resolving previous controversies about its structure and function.

Distinct gradients of cortical architecture capture visual representations and behavior across the lifespan

The paper shows two architectural gradients in human visual cortex that correlate with structural, functional, and behavioral traits across the lifespan.

Cognitive Control in Pediatric Cancer Survivors: A task-fMRI study

This study uses fMRI to compare brain activation during a cognitive task between pediatric cancer survivors exposed to chemotherapy and healthy controls, finding altered neural activation and cognitive control deficits in the chemo-exposed group.

High spatial resolution 23Na-MRI for ischemic brain injury detection

This study develops a high-resolution 23Na-MRI platform using implanted RF coils to detect ischemic brain injury with improved contrast-to-noise ratio.

An Open-Source, Excitation-Resolved UV-NIR Imaging Platform for Bioluminescence, Luminescence-Decay, and Chemical Discrimination Measurements

AURORA-MSI is an open-source multispectral imaging platform that enables excitation-resolved measurements of bioluminescence, luminescence decay, and chemical discrimination without photon-counting instrumentation.

The first comprehensive case study of early-emerging prosopometamorphopsia

This paper presents the first comprehensive case study of early-emerging prosopometamorphopsia, detailing its clinical manifestations and neural correlates.

Shared Pain, Shared Decisions: How Empathy Shapes Social Conformity Through Physiology and Visual Attention

This study investigates how empathy influences social conformity through physiological arousal, visual attention, and socio-emotional traits using a combination of behavioral and physiological measures.

Hexagonal modulation of theta rhythmic attentional sampling of visual space

The paper shows that visual attention samples space in a hexagonal pattern guided by theta rhythms, similar to spatial navigation mechanisms.

Bivalent habenula modulation of human monoaminergic midbrain and cortical pathways

This study uses fMRI and dynamic causal modelling to show the habenula modulates midbrain and cortical pathways with both inhibitory and excitatory effects during negative reward prediction error tasks.

Whole-body single-cell atlas of an adult vertebrate in homeostasis and regeneration

Region-stratified scRNA-seq of 607,370 cells plus 500-gene MERFISH maps adult Danionella cerebrum cell types body-wide, revealing fibroblast Hox and limb-identity programs and telencephalon regeneration dynamics.

Integrated luminescence and phenotypic profiling for drug discovery in a zebrafish model of Marfan syndrome

This study uses a zebrafish model of Marfan syndrome to identify potential therapies through a high-throughput drug screen and luminescence-based phenotyping.

Revealing the benefit of eye motion for acuity under emulated cone loss

The paper shows that eye motion compensates for cone loss in vision, maintaining acuity even with significant cone cell reduction.

A crown story: How tree architecture drives maple syrup yields

This study identifies crown structure and growth characteristics as key predictors of maple syrup yield, explaining up to 47% of inter-individual variability in syrup production.

OocystMeter, a machine-learning algorithm to count and measure Plasmodium oocysts, reveals clustering patterns in the Anopheles midgut

OocystMeter automates oocyst counting and sizing in mosquito midguts, revealing clustered spatial patterns in malaria infections.

Open Blink: Low-cost TIRF microscopy for super-resolutionimaging via μManager

Open Blink provides a low-cost, open-source TIRF microscope for quantitative multi-color super-resolution imaging with high localization precision and axial stability.

Data-driven gait cycle decomposition based on whole-body coordination dynamics

This study decomposes gait cycles using a dynamic system framework to identify coordination patterns in human locomotion.

Human brown adipose tissue demonstrates substantial 18F-fluorocholine uptake at room temperature for phosphatidylcholine synthesis

This study shows that 18F-fluorocholine PET can detect human brown adipose tissue at room temperature by measuring phosphatidylcholine synthesis, without requiring cold exposure.

Eg5 activity and density-driven bundling organize the human metaphase mitotic spindle independently of spindle bipolarity

The paper shows that Eg5 organizes antiparallel microtubule bundles in human metaphase spindles through density-driven steric interactions, independent of spindle bipolarity.

Species-specific oculomotor control tolerances explain saccadic suppression strength differences between macaques and zebrafish

The paper compares saccadic suppression strength between macaques and zebrafish, showing it reflects differences in sensory and motor noise levels and computational resource allocation.

DINOSim: Zero-Shot Object Detection and Semantic Segmentation on Microscopy Images

DINOSim detects and segments objects in microscopy images without annotated data, achieving performance comparable to supervised methods using a pretrained DINOv2 encoder and k-nearest neighbors refinement.

The elusive neural signature of emotion regulation capabilities: evidence from a large-scale consortium

This study examines the relationship between neural activation during reappraisal tasks and individual differences in emotion regulation, finding no shared overlap across three measures and highlighting methodological challenges in fMRI research.

Heightened gaze responsiveness and mutual gaze instability at close distances characterize dyadic coordination in a marmoset model of autism

This study examines dyadic coordination in a marmoset model of autism, finding heightened gaze responsiveness and unstable mutual gaze at close distances in affected pairs.

Eye gaze is not inversion-proof: A robust, sex-invariant gaze inversion effect

The paper investigates how face inversion affects sensitivity to gaze direction, finding a robust inversion effect that is largely sex-invariant.