Gut microbiota and health

This paper develops a novel in vitro culture medium, CF-MiPro, that mimics the CF gut environment and alters non-CF microbiomes to resemble CF-like profiles.

This study shows that deleting the Mup gene family in male mice alters their gut microbiota composition, reducing microbial diversity and specific beneficial taxa, while no such effect is observed in females.

MiCK is a database linking gut microbial genes to chemoresistance in cancer patients, providing 1.6 million sequences of 29 gene types curated from literature and sequence databases.

The paper shows a positive association between human height and gut microbiome diversity, linking it to CDI risk and suggesting vegetable intake can mitigate this effect.

This study identifies functional changes in the gut metagenome of individuals with moderate-to-severe asthma, including LCFA metabolism and antibiotic resistance gene enrichment.

The study identifies a disease-resistant BALB/c mouse substrain with a gut microbiota profile associated with reduced susceptibility to DSS-induced colitis.

This paper introduces a high-throughput protocol for cultivating gut microbiota to study responses to diet, drugs, and host factors.

This study investigates the factors influencing fecal particle size in humans and finds that gut microbiota, rather than diet or behavior, primarily shape particle size.

The paper develops a microfluidic model to study interactions between colonocytes, microbiota, and Fusobacterium nucleatum in a colorectal cancer microenvironment, showing altered gene expression and microbiota composition.

This study shows red cabbage juice modulates gut microbiota to improve intestinal homeostasis and reduce colitis in mice by enhancing SCFA production and suppressing inflammatory pathways.

This study identifies Akkermansia muciniphila as a key strain in fecal microbiota transplantation that alleviates gut barrier injury by modulating the Wnt/β-catenin signaling pathway in an ETEC infection model.

This study examines the association between homelessness and gut microbiome composition in Veterans, finding significant beta diversity differences and lower Akkermansia abundance in those with a history of homelessness.

This study examines how diet influences gut microbiome diversity, composition, and stability in a migratory bird, linking these factors to body mass gain during spring staging.

The paper develops a multi-omic prediction framework to diagnose IBD using metagenomic, metatranscriptomic, metabolomic, and viromic data, finding that metabolomics and viromics provide stronger predictive power than other omics.

This paper introduces frequentmers, a metagenomic feature for early disease detection, and applies it to identify liver cirrhosis with high accuracy using stool samples.

This study tracks the fecal and skin microbiota of two Mediterranean monk seal pups during rehabilitation, showing shifts in bacterial communities influenced by antibiotic treatment and probiotics.

The paper examines gut microbiome changes across different cardiovascular risk levels and in STEMI patients, identifying microbial species and pathways associated with cardiovascular risk and disease.

OBMeta provides a web server for analyzing and validating gut microbial features and biomarkers related to obesity and metabolic diseases through integrated metagenomics analysis and cross-validation of public datasets.

GDmicro improves disease status classification using gut microbiome data by combining semi-supervised learning and domain adaptation, achieving higher accuracy than existing methods.

This study profiles the transcriptome of human colonic cells exposed to SGG, showing it induces stronger transcriptional changes in cancerous HT29 cells than in normal FHC cells, with significant ER stress and UPR activation.

This study investigates how Bacteroides thetaiotaomicron's bile acid altering enzymes affect its fitness and metabolic transcriptome under bile acid exposure.

The paper describes the fecal microbiome of laboratory beagles before and after antiparasitic drug administration to assess in vivo versus in vitro bioequivalence.

This study examines the impact of peri-operative antibiotic prophylaxis on gut microbiota in horses undergoing median laparotomy, finding increased ESBL-producing bacteria and reduced diversity.

This study engineers E. coli to control H2S levels in a gut chip system, showing concentration-dependent effects on host gene expression and metabolism.

This paper shows loperamide induces dysbiosis in zebrafish microbiota by directly inhibiting bacterial growth.

The paper uses fecal metagenomics and machine learning to identify KEGG Orthology categories as biomarkers for food intake classification in controlled nutrition trials.

The paper examines how host admixture affects gut microbiota in house mice, finding weak effects after accounting for spatial autocorrelation.

This study uses hypogonadal mice to show sex and reproductive axis effects on intestinal microbial communities, with sex chromosomes also playing a role, and highlights limitations of fecal samples in reflecting small intestine diversity.

The paper investigates how bacterial populations in an IBD mouse model use sulfur metabolism and host nutrients to drive inflammation and sustain growth.

The paper shows acetate supplementation improves social deficits and changes gene expression in the prefrontal cortex of Shank3-deficient mice.