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This study shows that reducing Arf6 in endothelial cells impairs insulin-stimulated vasodilation and causes systemic insulin resistance.

This study shows that Kombucha Tea microbes reduce lipid accumulation in C. elegans by altering metabolic pathways and promoting lipid utilization.

This study shows that loss of cardiac PFKFB2 leads to metabolic, functional, and electrophysiological changes in the heart, including impaired systolic function and altered electrophysiology.

This study shows that post-surgical opioid use and surgery itself impair airway protection in cats, increasing aspiration pneumonia risk.

This study identifies MAO-B hyperactivation as a key contributor to cardiac dysfunction in MrgD-KO mice, showing that MAO-B inhibition reverses contractile defects.

The paper identifies metabolic and genetic adaptations in naked mole-rats that confer resistance to cardiovascular disease and hypoxia.

This paper models cardiorespiratory coherence during exercise anticipation, finding that sympathetic modulation, low vagal tone, and respiratory irregularity reduce coherence.

This study investigates sex-specific effects of beta-adrenergic activation on metabolic and inflammatory mediators in a murine model of post-traumatic osteoarthritis, finding sexually dimorphic gene expression and metabolic changes.

This study shows that TR{beta}-KO mice exhibit partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy when studied at thermoneutrality.

This study shows that MyBP-CC1C7 domains form C-links and stabilize myosin OFF states, affecting crossbridge kinetics and sarcomere function.

This study shows that foveal RGCs in primates develop altered calcium dynamics weeks after photoreceptor loss, with a significant decrease in calcium decay constant.

The paper shows that shrinking and shape-shifting in birds do not provide thermoregulatory benefits in a warming world, using experimental data on Japanese quail.

This study shows that eccentric resistance training increases serial sarcomere number and improves mechanical function in young rats but causes impairments in older rats.

This study compares the effects of semi-synthetic and grain-based diets on breeding outcomes and metabolic health in adult C57BL/6J mice, finding diet type influences body composition, fecal microbiota, and reproductive success.

The study shows that targeting synovial macrophages via STAT6 inhibition reduces pain in experimental knee OA without worsening joint damage.

This study characterizes the biophysical and neurophysiological effects of the SCN8A p.(Gly1625Arg) mutation, showing a complex mix of gain-and loss-of-function properties leading to reduced neuronal firing.

This study identifies a mechanism by which tardigrade CAHS D proteins form gels to protect cells during desiccation, showing that gelation reduces molecular motion and metabolic activity, with reversible effects.

This study compares glycogen pool utilisation during 1- and 15-minute maximal exercises and examines the effects of low carbohydrate intake on glycogen storage and usage.

This study shows circadian variation in mitochondrial complex I efficiency and core clock gene expression in hooded seal fibroblasts, linking circadian rhythms to mitochondrial function during hypoxia.

This study identifies Lac-Phe as a mediator of metformin's anti-obesity effects through experiments in mice and human cohorts.