A Host Enzyme Reduces Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) by Inactivating Intestinal Lipopolysaccharide
Z. Wang, N. Ojogun, Y. Liu, L. Gan, Z. Xiao, J. Feng, W. Jiang, Y. Chen, B. Zou, C. Yu, C. Li, A. Ashuo, X. Li, M. Fu, J. Wu, , M. Lu
This study shows that AOAH inactivates intestinal LPS, reducing MASLD by preventing hepatic lipid accumulation and altering lipid metabolism gene expression.
eLife · Apr 24, 2025Peer-reviewedImmunology