Author

A. Behren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:biophysical modeling· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. W. Purcell· 2 shared P. Faridi· 2 shared S. Ostrouska· 2 shared A. Anderson· 1 shared A. Chung· 1 shared A. Hammet· 1 shared A. P. Uldrich· 1 shared A. Peng· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

A. W. Purcell

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Author profile →

5 papers

Recent·Most cited

The circulating immune cell landscape stratifies metastatic burden in breast cancer patients

S. Mangiola, R. Brown, J. Berthelet, S. Guleria, C. Liyanage, S. Ostrouska, J. Wilcox, M. Merdas, P. F. Larsen, C. Bell, J. Schroder, L. Mielke, J. Mariadason, S. Chang-Hao Tsao, Y. Chen, , B. Pal

This study identifies immune cell signatures in peripheral blood that correlate with metastatic burden in breast cancer patients using single-cell transcriptomics.

bioRxiv · Nov 1, 2023 · PreprintCancer Biology

Vgamma9Vdelta2 T cells recognize butyrophilin 2A1 and 3A1 heteromers

T. S. Fulford, C. Soliman, R. G. Castle, M. Rigau, Z. Ruan, O. Dolezal, R. Seneviratna, H. G. Brown, E. Hanssen, A. Hammet, S. Li, S. J. Redmond, A. Chung, M. A. Gorman, M. W. Parker, , A. P. Uldrich

The paper reveals that Vgamma9Vdelta2 T cells recognize BTN2A1 and BTN3A1 heteromers through dual epitope engagement, uncovering a new mechanism of immune activation.

bioRxiv · Aug 30, 2023Immunology

A peptide-signal amplification strategy for the detection and validation of neoepitope presentation on cancer biopsies

S. H. Ramarathinam, P. Faridi, A. Peng, P. Szeto, N. C. Wong, A. Behren, M. Shackleton, A. W. Purcell

The paper develops a mass spectrometry-based method to detect HLA-bound peptides from tumor biopsies, enabling the identification of neoepitopes from as few as 1000 cells or 1 mg of tissue.

bioRxiv · Jun 12, 2020 · PreprintImmunology

Spliced peptides and cytokine driven changes in the immunopeptidome of melanoma

P. Faridi, K. Woods, S. Ostrouska, C. Deceneux, S. Q. Wong, W. Chen, R. Aranha, D. Duscharla, N. P. Croft, C. Li, R. Ayala, J. Cebon, A. W. Purcell, R. B. Schittenhelm, A. Behren

This study identifies spliced peptides and cytokine-driven changes in the immunopeptidome of melanoma, showing conserved immunogenic peptides across patients.

bioRxiv · Jun 1, 2020Immunology

A natural killer cell gene signature predicts melanoma patient survival

J. Cursons, F. Souza Fonseca Guimaraes, A. Anderson, M. Foroutan, S. Hediyeh Zadeh, A. Behren, N. D. Huntington, M. J. Davis

The paper develops an NK cell gene signature to predict survival in metastatic cutaneous melanoma patients using TCGA RNA-seq data.

bioRxiv · Aug 13, 2018 · PreprintCancer Biology