Author

A. El Daibani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

T. Che· 2 shared B. K. Kobilka· 1 shared B. Kobilka· 1 shared B. White· 1 shared C. Chen· 1 shared C. Sar· 1 shared C. Zhang· 1 shared E. O'Brien· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

T. Che

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 8, 2023

Negative allosteric modulation of the μ-opioid receptor

E. S. O'Brien, V. A. Rangari, A. El Daibani…·B. K. Kobilka

This paper identifies a negative allosteric modulator of the μ-opioid receptor that blocks agonist activity and enhances naloxone efficacy, offering potential for safer opioid overdose reversal.

DOI 10.1101/2023.09.08.556921

humanexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintApr 28, 2023

Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy

J. Zhao, M. Elgeti, E. O'Brien…·C. Chen

The paper uses biophysical techniques to show how ligand-induced conformational changes in the μ-opioid receptor affect its signaling efficacy.

DOI 10.1101/2023.04.28.538657

experimental assaybiophysical modeling

𝕏 PostBluesky