Author

A. Fitzpatrick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Animal Behavior & Cognition· 1 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Li· 1 shared A. Mills· 1 shared A. Mohammed· 1 shared A. N. J. Tutt· 1 shared C. Isacke· 1 shared C. N. Cook· 1 shared C. Selva· 1 shared D. Feng· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBioengineering

A. Li

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

HIGH THROUGHPUT QUANTITATION OF HUMAN NEUTROPHIL RECRUITMENT AND FUNCTIONAL RESPONSES IN AN AIR-BLOOD BARRIER ARRAY

H. Viola, L. H. Chen, S. Jo, K. Washington, C. Selva, A. Li, D. Feng, V. Giacalone, S. Stephenson, K. Cottrill, A. Mohammed, E. Williams, X. Qu, W. A. Lam, N. L. Ng, , S. Takayama

The paper develops a high-throughput assay to study neutrophil recruitment and function in an air-blood barrier array, showing improved throughput and sample efficiency compared to existing methods.

bioRxiv · May 10, 2024Bioengineering

Genomic profiling and pre-clinical modelling of breast cancer leptomeningeal metastasis reveals acquisition of a lobular-like phenotype

A. Fitzpatrick, M. Iravani, A. Mills, D. Vicente, T. Alaguthurai, I. Roxanis, N. C. Turner, S. Haider, A. N. J. Tutt, C. Isacke

This study analyzes genomic changes in breast cancer leptomeningeal metastasis using CSF samples, identifying unique genetic features and potential therapeutic targets.

bioRxiv · Jan 20, 2023Cancer Biology

Design of an ultrafast pulsed ponderomotive phase plate for cryo-electron tomography

D. X. Du, A. Fitzpatrick

The paper designs an ultrafast pulsed ponderomotive phase plate for cryo-electron tomography, showing that picosecond laser pulses can generate high fluences for phase shifts without Kapitza-Dirac diffraction effects.

bioRxiv · May 9, 2022Biophysics

Evaluation of Cognitive Function in the Dog Aging Project: Associations with Baseline Canine Characteristics

S. Yarborough, A. Fitzpatrick, S. Schwartz, Dog Aging Project Consortium

This study evaluates cognitive function in aging dogs using a large cohort, finding age, activity level, and health history are associated with canine cognitive dysfunction.

bioRxiv · May 4, 2022Animal Behavior & Cognition

Role of molecular polymorphism in defining tau filament structures in neurodegenerative diseases

X. Xiang, T. Arakhamia, Y. Carlomagno, S. Dhingra, M. Thierry, M. DeTure, C. N. Cook, D. W. Dickson, L. Petrucelli, A. Fitzpatrick

This study determines the structure of twisted tau filaments in progressive supranuclear palsy and compares them to tau folds in corticobasal degeneration, identifying molecular polymorphism as a factor in filament morphology.

bioRxiv · May 24, 2021 · PreprintBiophysics