D. Feng

HIGH THROUGHPUT QUANTITATION OF HUMAN NEUTROPHIL RECRUITMENT AND FUNCTIONAL RESPONSES IN AN AIR-BLOOD BARRIER ARRAY

The paper develops a high-throughput assay to study neutrophil recruitment and function in an air-blood barrier array, showing improved throughput and sample efficiency compared to existing methods.

Recombinant expression, purification, and antifungal activity of the novel antimicrobial peptide TaW662

This study identifies and characterizes TaW662, an antifungal peptide from wheat, showing inhibition of Blumeria graminis f. sp. tritici growth and potential as a fungicide.

Identification and functional analysis of eRNA markers for hepatocellular carcinoma based on high-throughput data

This study identifies three eRNA biomarkers for hepatocellular carcinoma (HCC) and shows their involvement in cancer progression, prognosis, and potential as therapeutic targets.

Discovery and characterization of cross-reactive intrahepatic antibodies in severe alcoholic hepatitis

This study identifies cross-reactive intrahepatic antibodies in severe alcoholic hepatitis that target both bacterial antigens and human proteins, suggesting a role in disease pathogenesis.

A Self-Healing, Viscoelastic Hydrogel Promotes Healing of Brain Lesions

This paper develops a self-healing hydrogel that mimics brain parenchyma viscoelasticity to promote healing of brain lesions in mice.

Analysis of rhizosphere bacterial diversity of Angelica dahurica var. formosana based on different experimental sites and varieties (strains)

This study analyzes rhizosphere bacterial diversity of Angelica dahurica var. formosana across different sites and varieties, finding stable communities and key taxa linked to yield and quality.

Chitinase 3-like-1 Contributes to Acetaminophen-induced Liver Injury by Promoting Hepatic Platelet Recruitment

This study identifies Chi3l1 as a key mediator of acetaminophen-induced liver injury by promoting hepatic platelet recruitment through the CD44 axis.

Deacetylation of IFIT2 mediated by HDAC5 promotes the stemness and progression of glioma

This study shows that HDAC5 deacetylates IFIT2, promoting glioma stemness and progression by inducing IFIT2 ubiquitination and loss of anti-tumor activity.

TCR signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 NPC subcomplex via phosphorylation of RanGAP1 by PKC-θ

This study shows that PKC-θ phosphorylates RanGAP1 to promote its sumoylation and assembly with RanBP2 and Ubc9, facilitating nuclear import of AP-1.

Thinopyrum intermedium TiAP1 interacts with a chitin deacetylase from Blumeria graminis f. sp. tritici and increases the resistance to Bgt in wheat

This study identifies TiAP1 from Thinopyrum intermedium as a resistance gene against Blumeria graminis f. sp. tritici, showing it interacts with BgtCDA1 and enhances wheat resistance through immune activation.

Modeling of symbiotic bacterial biofilm growth with an example of the Streptococcus-Veillonella sp. system

The paper develops a mathematical model to simulate symbiotic biofilm growth using Streptococcus-Veillonella as an example, showing how initial biomass distribution affects homogenization.

Cerebrospinal fluids from healthy pregnant women does not harbor a detectable microbial community

This study analyzes cerebrospinal fluid from healthy pregnant women and finds no evidence of a detectable microbial community after accounting for contamination.

MicroRNA-224 Promotes Cell Migration and Invasion by Targeting HOXA5 expression in Hepatocellular Carcinoma

This study shows miR-224 promotes HCC cell migration and invasion by targeting HOXA5 and ADAM17, suggesting it as a potential therapeutic target.

Single-Cell Map of Diverse Immune Phenotypes in the Metastatic Brain Tumor Microenvironment of Non Small Cell Lung Cancer

The paper uses single-cell RNA sequencing to analyze immune cell composition in brain metastases of NSCLC patients, finding reduced T cell activity and expanded M2-polarized tumor-associated macrophages.