A. Goossens

The selective estrogen receptor modulator clomiphene inhibits sterol biosynthesis in Arabidopsis thaliana

The paper identifies clomiphene, a selective estrogen receptor modulator, as an inhibitor of plant sterol biosynthesis by targeting CPI1, suggesting its potential for agricultural applications.

Conserved and newly acquired roles of PIF1 homologs in tomato (Solanum lycopersicum)

This study examines PIF1 homologs in tomato, showing conserved and new roles compared to Arabidopsis, with PIF1a having additional functions in root hair elongation and fruit development.

Subfunctionalization of paralog transcription factors contributes to regulation of alkaloid pathway branch choice in Catharanthus roseus

The paper identifies subfunctionalization of ORCA transcription factors in Catharanthus roseus, revealing their role in regulating specific branches of the alkaloid pathway and their interaction with MYC2.

Establishment of Proximity-dependent Biotinylation Approaches in Different Plant Model Systems

The paper establishes TurboID as the most effective PDL method in plant systems and demonstrates its utility in capturing protein interactomes and structural information.

SlKIX8 and SlKIX9 are negative regulators of leaf and fruit growth in tomato

This study identifies SlKIX8 and SlKIX9 as negative regulators of leaf and fruit growth in tomato, with loss-of-function mutants showing enlarged organs due to increased cell expansion.

Constitutive Steroidal Glycoalkaloid Biosynthesis in Tomato is Regulated by the Clade IIIe Basic Helix-Loop-Helix Transcription Factors MYC1 and MYC2

The paper shows that MYC1 and MYC2 control constitutive steroidal glycoalkaloid biosynthesis in tomato independently of jasmonate signaling.

ER-Anchored Transcription Factors bZIP17 and bZIP60 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula

ER stress bZIP transcription factors interfere with jasmonate-inducible bHLH transcription factors to modulate plant specialized metabolism under stress.

The use of mutants and inhibitors to study sterol biosynthesis in plants

This paper reviews the complexity of plant sterol biosynthesis pathways and discusses the use of human and yeast inhibitors in plants to develop tailored sterol biosynthesis inhibitors.

A dual sgRNA approach for functional genomics in Arabidopsis thaliana

The paper introduces a dual sgRNA CRISPR/Cas9 approach to generate reliable loss-of-function alleles in Arabidopsis thaliana, improving the generation of true null alleles for functional genomics.