Author

A. Grimson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

E. A. Fogarty· 2 shared A. Dziubek· 1 shared A. McIntyre· 1 shared A. Simkin· 1 shared B. A. Keller· 1 shared B. Rudd· 1 shared C. F. R. Ascencao· 1 shared C. J. Franconi· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

E. A. Fogarty

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Author profile →

4 papers

Recent·Most cited

A TOPBP1 Allele Causing Male Infertility Uncouples XY Silencing Dynamics From Sex Body Formation

C. F. R. Ascencao, J. Sims, A. Dziubek, W. Comstock, E. A. Fogarty, J. Badar, R. Freire, A. Grimson, R. S. Weiss, P. E. Cohen, M. B. Smolka

This study identifies a TOPBP1 mutation causing male infertility by disrupting ATR-dependent MSCI dynamics without affecting SB formation.

eLife · Feb 23, 2024Peer-reviewedCell Biology

Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

F. Ahmed, L. T. Vu, H. Zhu, D. S. H. Iu, E. A. Fogarty, Y. Kwak, W. Chen, C. J. Franconi, P. R. Munn, S. M. Levine, J. Stevens, X. Mao, D. C. Shungu, G. E. Moore, B. A. Keller, , A. Grimson

This study uses single-cell RNA-seq to analyze immune cells in ME/CFS patients at baseline and after exercise, identifying dysregulated monocytes and platelet transcriptomes.

bioRxiv · Oct 13, 2022 · PreprintImmunology

Lin28b specifies an innate-like lineage of CD8+ T cells in early life

N. Watson, R. Patel, O. Oyesola, N. Laniewski, J. Grenier, J. Wang, C. Tabilas, K. J. Y. Mon, S. Peng, S. Wesnak, K. Nzingha, N. Smith, M. Davenport, E. T. Wojno, K. Scheible, , B. Rudd

The paper shows Lin28b programs neonatal CD8+ T cells to have innate defense capabilities through transcriptional and epigenetic changes.

bioRxiv · Feb 14, 2022 · PreprintImmunology

Evolutionary Dynamics of microRNA target sites across vertebrate evolution

A. Simkin, R. Geissler, A. McIntyre, A. Grimson

This paper quantifies selective pressures on miRNA target sites across vertebrate evolution, revealing distinct evolutionary patterns among miRNAs.

bioRxiv · Jul 4, 2019Evolutionary Biology