F. Ahmed

Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

This study uses single-cell RNA-seq to analyze immune cells in ME/CFS patients at baseline and after exercise, identifying dysregulated monocytes and platelet transcriptomes.

Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of Parkinson's disease

This study shows that inhibiting NAAA, which deactivates PEA, protects dopamine neurons and reduces Parkinson's symptoms in mouse models.

Peptidoglycan recycling contributes to outer membrane integrity and carbapenem tolerance in Acinetobacter baumannii

This study identifies peptidoglycan recycling as a mechanism contributing to outer membrane integrity and carbapenem tolerance in Acinetobacter baumannii.

Repurposing melanoma chemotherapy to activate inflammasomes in treatment of BRAF/MAPK inhibitor-resistant melanoma

This study shows that temozolomide combined with chloroquine can induce pyroptosis in BRAF/MAPK inhibitor-resistant melanoma by activating different inflammasomes.

Neurotrophin signaling is modulated by specific transmembrane domain interactions

The paper identifies and characterizes the direct interaction between TrkA and p75 through their transmembrane domains, showing its role in TrkA activation and cell differentiation.

Development of Equine Immunoglobulin Fragment F(ab')2 with High Neutralizing Capability against SARS-CoV-2

This study develops equine-derived F(ab')2 antibodies with high neutralizing capability against SARS-CoV-2, showing effectiveness against viral variants.

Hydrogen-deuterium exchange reveals a dynamic DNA binding map of Replication Protein A

This study uses HDX-MS to analyze the dynamic DNA binding properties of RPA domains, revealing that DBD-C is most involved in stabilizing RPA on ssDNA.

PCB126-mediated effects on adipocyte energy metabolism and adipokine secretion may result in abnormal glucose uptake in muscle cells

This study shows PCB126 exposure impairs glucose uptake in muscle cells by altering adipokine secretion and mitochondrial function in insulin-resistant adipocytes.

Population density modeling of mixed polymorphic phenotypes: an application of spatial mark-resight models

This study applies spatial mark-resight models to estimate leopard densities in Manas National Park, incorporating both melanistic and wild phenotypes using camera trap data.

Identification of radiation responsive proteins from Spleen and Intestine tissue of mice using Mass Spectrometry approach.

The paper identifies radiation-responsive proteins in mouse spleen and intestine using mass spectrometry and assesses Podophyllotoxin's protective effect against radiation injury.

Decoding age-related changes in the spatiotemporal neural processing of speech using machine learning

This study uses machine learning to analyze spatiotemporal neural responses to speech in older adults with and without hearing loss, identifying distinct brain networks and regions involved in speech perception under different conditions.

Developmental exposure to pesticide contaminated food impedes bumblebee brain growth predisposing adults to become poorer learners

This study shows that pesticide exposure during development impairs bumblebee brain growth and learning ability in adulthood.