J. Stevens

Leveraging the genetic diversity of trout in the rivers of the British Isles and northern France to understand the movements of sea trout (Salmo trutta L.) around the English Channel

This study uses genetic markers to track movements of sea trout in the English Channel and southern North Sea, revealing both local and long-distance migration patterns.

Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns

This study identifies microbiota-derived inosine as a key factor in promoting CD8+ T cell responses against influenza in newborns by reversing epigenetic dysregulation.

Probing the stability and interdomain interactions in the ABC transporter OpuA, using single-molecule optical tweezers

The paper uses single-molecule optical tweezers to study the dynamics and interdomain interactions of the ABC transporter OpuA in lipid nanodiscs.

Investigating the role of Mce proteins in Mycobacterium avium paratuberculosis infection

This study identifies Mce1A and Mce1D as effector molecules in MAP that enhance bacterial attachment and invasion in specific cell types.

Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

This study uses single-cell RNA-seq to analyze immune cells in ME/CFS patients at baseline and after exercise, identifying dysregulated monocytes and platelet transcriptomes.

Development of 3D bovine intestinal organoid derived models to investigate Mycobacterium avium ssp paratuberculosis pathogenesis

This study develops 3D bovine intestinal organoid models to study Mycobacterium avium ssp. paratuberculosis infection and finds that C49 is more invasive than K10 in these models.

Engineering a Vaccine Platform using Rotavirus A to Express SARS-CoV-2 Spike Epitopes

This paper tests engineering rotavirus to express SARS-CoV-2 spike epitopes, finding that inserting peptides into NSP3 is feasible while VP4 insertions impair viral replication.

Balance between protective and pathogenic immune responses to pneumonia in the neonatal lung enforced by gut microbiota.

The paper shows that gut microbiota balance immune responses in neonatal lungs, promoting recovery from pneumonia by modulating tissue repair and inflammation.