Author

J. Grenier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

A. G. Clark· 1 shared A. Grimson· 1 shared A. K. Dube· 1 shared B. Rudd· 1 shared C. R. Landry· 1 shared C. Tabilas· 1 shared D. Melo· 1 shared E. T. Wojno· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperEvolutionary Biology

A. G. Clark

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Author profile →

3 papers

Recent·Most cited

Longitudinal sequencing reveals polygenic andepistatic nature of genomic response to selection

S. K. G. Forsberg, D. Melo, J. Grenier, S. Wolf, M. Tang, L. Henry, L. F. Pallares, A. G. Clark, J. F. Ayroles

This study uses longitudinal sequencing in Drosophila to show that genomic response to selection involves both polygenic shifts and epistatic interactions, with DEGs enriched for selected SNPs.

bioRxiv · Jul 22, 2024Evolutionary Biology

Compensatory mutations potentiate constructive neutral evolution by gene duplication

P. C. Despres, A. K. Dube, J. Grenier, M.-E. Picard, R. Shi, C. R. Landry

The paper duplicates and evolves an homodimeric enzyme to show that compensatory mutations can lead to functional heteromers through subfunctionalization.

bioRxiv · Feb 12, 2024Evolutionary Biology

Lin28b specifies an innate-like lineage of CD8+ T cells in early life

N. Watson, R. Patel, O. Oyesola, N. Laniewski, J. Grenier, J. Wang, C. Tabilas, K. J. Y. Mon, S. Peng, S. Wesnak, K. Nzingha, N. Smith, M. Davenport, E. T. Wojno, K. Scheible, , B. Rudd

The paper shows Lin28b programs neonatal CD8+ T cells to have innate defense capabilities through transcriptional and epigenetic changes.

bioRxiv · Feb 14, 2022 · PreprintImmunology