Author

A. Hyrenius-Wittsten

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Immunology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Liu· 1 shared G. Montgomery· 1 shared J. M. Garcia· 1 shared K. T. Roybal· 1 shared M. Park· 1 shared N. Perry· 1 shared Y. Su· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

B. Liu

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJan 6, 2021

Enhanced Solid Tumor Recognition and T cell Stemness with SynNotch CAR Circuits

A. Hyrenius-Wittsten, Y. Su, M. Park…·K. T. Roybal

This study identifies ALPPL2 as a tumor-specific antigen and demonstrates that synNotch CAR T cells targeting it improve tumor control by reducing T cell exhaustion.

DOI 10.1101/2021.01.06.425642

humanproteomics

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