BRWD1 orchestrates chromatin topology by converting static to dynamic cohesin complexes
M. Mandal, M. Maienschein-Cline, Y. Hu, A. Mohsin, M. L. Veselits, N. E. Wright, M. K. Okoreeh, Y. m. Yoon, J. Veselits, K. Georgopoulos, M. Clark
The paper shows BRWD1 converts static to dynamic cohesin complexes in pre-B cells, enabling chromatin topology changes needed for cell fate transitions.
bioRxiv · Jan 23, 2023 · PreprintImmunology