M. R. Clark

This paper applies Bayesian Networks to assess ecological risks of deep-sea mining on Chatham Rise, identifying uncertainties and informing policy decisions.

This study shows STAT3 signaling in B cells controls germinal center zone organization and recycling, affecting long-lived plasma cell and memory B cell output.

Using deep machine learning to analyze confocal microscopy data, the study shows CD4-T cell populations in lupus nephritis organize into spatial neighborhoods predicting renal failure progression.

The paper identifies a unique B cell subset in renal allograft rejection that contributes to local inflammation through self-reactive antibodies and innate-like signaling.

The paper shows that anti-vimentin antibodies in lupus nephritis undergo in situ selection for enhanced binding and specificity to vimentin fibrils, challenging the notion of affinity maturation as a non-specific consequence of polyreactivity.

This study shows that B-1a cells bypass the pre-BCR selection stage by developing in fetal liver with reduced IL-7R/STAT5 levels, leading to self-reactive BCRs.