R. Abraham

Interferon-Induced PARP14-Mediated ADP-Ribosylation in p62 Bodies Requires an Active Ubiquitin-Proteasome System

This study shows interferon induces ADP-ribosylation in p62 bodies via PARP14, requiring ubiquitin activation and proteasome activity.

Escherichia coli isolated from commercial layer hens in Australia remain susceptible to critically important antimicrobials

This study assesses antimicrobial resistance in Escherichia coli from Australian layer hens, finding low resistance rates likely due to strict antimicrobial use controls.

A Suite of Advanced Tutorials for the WESTPA 2.0 Rare-Events Sampling Software

The paper provides advanced tutorials for WESTPA 2.0, demonstrating new features for rare-events sampling in molecular simulations.

Proximity to human settlement is directly related to carriage of critically important antimicrobial-resistant Escherichia coli and Klebsiella pneumoniae in Silver Gulls

This study finds that Silver Gulls near human settlements carry more critically important antimicrobial-resistant E. coli and K. pneumoniae than those in remote areas.

In lupus nephritis, specific in situ inflammatory states are associated with refractory disease and progression to renal failure

Using deep machine learning to analyze confocal microscopy data, the study shows CD4-T cell populations in lupus nephritis organize into spatial neighborhoods predicting renal failure progression.

Validation of selective agars for detection and quantification of Escherichia coli resistant to critically important antimicrobials

This study identifies optimal selective agars and antimicrobial combinations for detecting and quantifying resistant Escherichia coli using designed experiments and statistical analysis.

Robotic Antimicrobial Susceptibility Platform (RASP): A Next Generation Approach to One-Health Surveillance of Antimicrobial Resistance.

The paper introduces a robotic platform for high-throughput antimicrobial resistance surveillance, showing it matches human performance and identifies diverse AMR phenotypes in gut E. coli.

In situ humoral selection in human lupus tubulointerstitial inflammation

The paper shows that anti-vimentin antibodies in lupus nephritis undergo in situ selection for enhanced binding and specificity to vimentin fibrils, challenging the notion of affinity maturation as a non-specific consequence of polyreactivity.

Examination of Australian Streptococcus suis Isolates From Clinically Affected Pigs in a Global Context and the Genomic Characterisation of ST1 as a Predictor of Virulence

The paper analyzes 148 Australian Streptococcus suis isolates from pigs, comparing their genomic features and virulence genes to global isolates, identifying ST1 as a virulence predictor.