Cell BiologybioRxiv
CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia
S. Dinakaran, H. Zhao, Y. Tang…·P. Marambaud
This study identifies CDK6-driven cell cycle acceleration in endothelial cells as a driver of arteriovenous malformations in HHT, suggesting CDK4/6 inhibitors as potential therapeutic options.