Author

G. Chao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. H. M. Ng· 1 shared A. Imran· 1 shared A. Pasculescu· 1 shared A. Polyzois· 1 shared A. Pu· 1 shared A.-C. Gingras· 1 shared B. van Sambeek· 1 shared C. Kovacs· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBioengineering

A. H. M. Ng

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Author profile →

3 papers

Recent·Most cited

Mining for disease-associated microbial metabolites in an age-dependent model of multiple sclerosis

A. Pu, N. Fettig, A. Polyzois, G. Chao, I. Naouar, L. Hohman, M. A. Fontaine, M. Zuo, K. Champagne-Jorgensen, J. Copeland, D. Chan, K. M. Davis, R. Yu, S. Popple, N. A. Carranza Garcia, , L. C. Osborne

The paper identifies a microbial metabolite, indole 3-propionic acid, that can reverse non-remitting EAE in aged mice, suggesting therapeutic potential for progressive MS.

bioRxiv · May 27, 2024 · PreprintImmunology

Immunogenicity of COVID-19 vaccines and their effect on the HIV reservoir in older people with HIV

V. A. Matveev, E. Z. Mihelic, E. Benko, P. Budylowski, S. Grocott, T. Lee, C. S. Korosec, K. Colwill, H. Stephenson, R. Law, L. A. Ward, S. Sheikh-Mohamed, G. Mailhot, M. Delgado-Brand, A. Pasculescu, , M. Ostrowski

This study evaluates the immunogenicity of COVID-19 vaccines in older people with HIV and their impact on HIV reservoirs, finding that three doses are needed for optimal neutralizing responses but vaccines may increase HIV reservoirs in those with persistent viremia.

bioRxiv · Jun 14, 2023Immunology

Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC

S. Liu, L. Li, F. Zhang, B. van Sambeek, E. Appleton, A. H. M. Ng, P. Khoshakhlagh, Y. Chen, M. Garcia-Corral, C.-T. Wu, J. Y. Huang, Y. Tan, G. Chao, J. Aach, J. Tam, , G. Church

This study uses iterative transcription factor screening to generate microglia-like cells from human iPSCs, identifying a combination of TFs that efficiently differentiate iPSCs into microglia-like cells within 4 days.

bioRxiv · Jun 3, 2022Bioengineering