Human CCR6+ Th cells show both an extended stable gradient of Th17 activity and imprinted plasticity
S. P. Singh, F. Parween, N. Edara, H. H. Zhang, J. Chen, F. Otaizo-Carrasquero, D. Cheng, N. A. Oppenheim, A. Ransier, W. Zhu, A. Shamsaddini, P. J. Gardina, S. W. Darko, T. P. Singh, D. C. Douek, , J. M. Farber
The paper identifies an extended gradient of Th17 activity in human CCR6+ Th cells, showing both stable phenotypes and plasticity under different activation conditions.
bioRxiv · Jan 5, 2023Immunology