Author

A. S. Kumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. Jones· 2 shared H. Zhou· 2 shared M. Duquette· 2 shared M. J. O'Melia· 2 shared P. Huang· 2 shared P.-J. Lei· 2 shared S. Chatterjee· 2 shared T. P. Padera· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

D. Jones

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Author profile →

3 papers

Recent·Most cited

Lymphatic muscle cells are unique cells that undergo aging induced changes

P.-J. Lei, K. J. Ruscic, K. Roh, J. J. Rajotte, M. J. O'Melia, E. M. Bouta, M. Marquez, E. R. Pereira, A. S. Kumar, G. Arroyo-Ataz, M. S. Razavi, H. Zhou, L. Menzel, H. Kumra, M. Duquette, , T. P. Padera

This study creates a single-cell transcriptomic atlas of lymphatic muscle cells in mice across ages, revealing age-related transcriptional changes and a pro-inflammatory environment in aged cells.

bioRxiv · Nov 18, 2023Cell Biology

Breast cancer progression and metastasis to lymph nodes reveals cancer cell plasticity and MHC class II-mediated immune regulation

P.-J. Lei, E. Pereira, P. Andersson, Z. Amoozgar, J. W. V. Wijnbergen, M. J. O'Melia, H. Zhou, S. Chatterjee, W. W. Ho, J. M. Posada, A. S. Kumar, S. Morita, C. Chuang, I. Ergin, D. Jones, , T. P. Padera

This study identifies MHC class II expression in metastatic breast cancer cells and shows its role in immune evasion and tumor progression through IFN-gamma and JAK/STAT signaling.

bioRxiv · Oct 30, 2022Cancer Biology

Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma

M. Datta, S. Chatterjee, E. M. Perez, S. Gritsch, S. Roberge, M. Duquette, I. X. Chen, K. Naxerova, A. S. Kumar, M. Ghosh, K. E. Emblem, M. R. Ng, W. W. Ho, P. Kumar, S. Krishnan, , R. K. Jain

Losartan prevents ICB-induced cerebral edema and improves survival in glioblastoma mice, with a predictive immune signature identified.

bioRxiv · Jun 28, 2022 · PreprintCancer Biology