Author

Z. Amoozgar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

P. Huang· 3 shared D. Fukumura· 2 shared P. Andersson· 2 shared P.-J. Lei· 2 shared R. Jain· 2 shared A. Matsui· 1 shared A. S. Kumar· 1 shared C. Chuang· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

P. Huang

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3 papers

Recent·Most cited

Cancer BiologybioRxivJan 26, 2023

Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy

J. Chen, Z. Amoozgar, X. LIU…·D. G. Duda

This paper shows that combining chemotherapy with CTLA-4 blockade reprograms the immune microenvironment of intrahepatic cholangiocarcinoma, enhancing the effectiveness of anti-PD1 therapy.

DOI 10.1158/2326-6066.cir-23-0486

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivOct 30, 2022

Breast cancer progression and metastasis to lymph nodes reveals cancer cell plasticity and MHC class II-mediated immune regulation

P.-J. Lei, E. Pereira, P. Andersson…·T. P. Padera

This study identifies MHC class II expression in metastatic breast cancer cells and shows its role in immune evasion and tumor progression through IFN-gamma and JAK/STAT signaling.

DOI 10.1084/jem.20221847

humanmouse

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Cancer BiologybioRxivPreprintSep 3, 2022

Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells

Z. Amoozgar, J. Ren, N. Wang…·R. Jain

This study shows that blocking VEGF, Ang2, and PD1 reprograms GBM endothelial cells into quasi-antigen-presenting cells, enhancing anti-tumor responses and controlling edema.

DOI 10.1101/2022.09.03.506476

humanorganoid / primary culture

𝕏 PostBluesky