R. K. Jain

This study analyzes genetic diversity in Thar Desert communities, revealing migration, cultural influences, and admixture shaping their genetic landscape.

This study profiles metabolites in renal cell carcinoma tissue and fluid to show that nutrient availability is more influenced by tissue-specific factors than tumor-driven changes.

This study shows losartan improves chemo-immunotherapy effectiveness in ovarian cancer by altering the tumor microenvironment and reducing IGF-1 signaling in cancer cells.

Losartan prevents ICB-induced cerebral edema and improves survival in glioblastoma mice, with a predictive immune signature identified.

The paper screens a compound library across invertebrate and human models of mucolipidosis IV to identify conserved disease modifiers, finding cyclin-dependent kinase inhibition as a potential therapeutic strategy.

This study shows that brain metastases rely on PHGDH-mediated serine synthesis due to limited environmental serine, making them sensitive to PHGDH inhibition.

This paper demonstrates that FDA-approved NIR dyes like ICG can be used for SWIR fluorescence imaging in vivo, enabling high-contrast imaging beyond 1500 nm with potential clinical applications.