Author

A. Sakamoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Crespillo-Casado· 1 shared A. Hirabayashi· 1 shared A. Zyryanova· 1 shared C. R. Esteban· 1 shared C. Rato· 1 shared D. Ron· 1 shared E. Nunez-Delicado· 1 shared E. Sano· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Crespillo-Casado

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

F. Hatanaka, K. Suzuki, K. Shojima, J. Yu, Y. Takahashi, A. Sakamoto, J. Prieto, M. Shokhirev, C. R. Esteban, E. Nunez-Delicado, J. C. I. Belmonte

The paper combines gene supplementation and genome editing to treat spinal muscular atrophy in mice, showing long-term therapeutic benefits.

bioRxiv · Apr 6, 2023Bioengineering

Modeling SARS-CoV-2 infection and its individual differences with ACE2-expressing human iPS cells

E. Sano, A. Sakamoto, N. Mimura, A. Hirabayashi, Y. Muramoto, T. Noda, T. Yamamoto, K. Takayama

This study uses ACE2-expressing human iPS cells to model SARS-CoV-2 infection and shows sex-based differences in viral production.

bioRxiv · Feb 22, 2021Cell Biology

ISRIB blunts the integrated stress response by allosterically antagonising the inhibitory effect of phosphorylated eIF2 on eIF2B

A. Zyryanova, K. Kashiwagi, C. Rato, H. P. Harding, A. Crespillo-Casado, L. Perera, A. Sakamoto, M. Nishimoto, M. Yonemochi, M. Shirouzu, T. Ito, D. Ron

This study shows ISRIB inhibits the integrated stress response by antagonizing eIF2(P)-induced inhibition of eIF2B through allosteric effects.

bioRxiv · Sep 28, 2020Biochemistry