Author

A. Speed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

C. Frezza· 2 shared A. N. Mora· 1 shared C. Rogerson· 1 shared C. Schmidt· 1 shared C. Yong· 1 shared D. Adams· 1 shared E. R. Maher· 1 shared F. Joud· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

C. Frezza

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues.

M. Kamp, J. Surmacki, M. Segarra Mondejar, T. Young, K. Chrabaszcz, F. Joud, V. Zecchini, A. Speed, C. Frezza, S. Bohndiek

This paper uses Raman micro-spectroscopy to directly detect and map fumarate distribution in living cells and tissues, revealing its compartmentalization and distinguishing Fh1-deficient cells.

bioRxiv · Jul 2, 2023Cell Biology

HIRA loss transforms FH-deficient cells

L. Valcarcel-Jimenez, C. Rogerson, C. Yong, C. Schmidt, M. Yang, V. Harle, V. Offord, K. Wong, A. N. Mora, A. Speed, V. Caraffini, M. G. B. Tran, E. R. Maher, G. D. Stewart, S. Vanharanta, , C. Frezza

This study identifies HIRA depletion as a factor that enhances proliferation and invasion of Fh1-deficient cells, revealing a mechanism involving MYC activation and nucleotide metabolism.

bioRxiv · Jun 4, 2022Cancer Biology