Author

A. A. Kuehl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

B. Siegmund· 2 shared A. Egners· 1 shared A. Fragoulis· 1 shared A. Huck· 1 shared A. Petersen· 1 shared A. Thiel· 1 shared B. Obermayer· 1 shared B. Sawitzki· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

B. Siegmund

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 15, 2023

Osteopontin in colitis-associated carcinoma

S. Manna, M. Sehn, D. Cardoso da Silva…·M. Schumann

This study investigates the role of osteopontin (SPP1/OPN) in colitis-associated carcinoma (CAC) using a multi-omics approach, revealing its indirect immunosuppressive role in the tumor microenvironment.

DOI 10.1101/2023.12.15.571952

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivSep 18, 2022

HDAC7 controls anti-viral and anti-tumor immunity by CD8+ T cells

C. Yerinde, J. Keye, S. Durlanik…·C. Weidinger

This study shows HDAC7 regulates CD8+ T cell function by controlling survival, calcium homeostasis, and memory responses, impacting anti-viral and anti-tumor immunity in mice.

DOI 10.3389/fimmu.2026.1816695

mousegenetic perturbation / CRISPR

𝕏 PostBluesky

ImmunologybioRxivPreprintApr 20, 2021

TCAIM controls effector T cell generation by preventing Mitochondria-Endoplasmic Reticulum Contact Site-initiated Cholesterol Biosynthesis

C. Iwert, J. Stein, C. Appelt…·B. Sawitzki

This study shows TCAIM prevents effector T cell differentiation by inhibiting mitochondria-ER contact sites that drive cholesterol biosynthesis and HIF1 activation.

DOI 10.1101/2021.04.20.440500

mouseproteomics

𝕏 PostBluesky

Cancer BiologybioRxivFeb 28, 2018

Non-canonical HIF-1 stabilization is essential for intestinal tumorigenesis

N. Rohwer, S. Jumpertz, M. Erdem…·T. Cramer

This study shows that non-canonical HIF-1 stabilization is crucial for intestinal tumorigenesis, independent of hypoxia, by affecting both epithelial and microenvironmental oncogenic processes.

DOI 10.1038/s41388-019-0816-4

mouseexperimental assay

𝕏 PostBluesky