Cell BiologybioRxiv
Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction
Y.-T. Yeh, C. Sona, X. Yan…·M. N. Poy
The paper shows restoring PITPNA in T2D human islets reverses beta-cell dysfunction by improving insulin granule maturation and glucose-stimulated insulin secretion.