Author

A. Wilhelm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

F. Roesmann· 2 shared M. Widera· 2 shared A. A. Kuehl· 1 shared A. Kuenkele· 1 shared A. L. Siemund· 1 shared A. M. Jacobi· 1 shared A. Pruss· 1 shared A. Rehm· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

F. Roesmann

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Intestinal interstitial fluid isolation provides novel insight into the human host-microbiome interface

E. G. Avery, L.-M. Haag, V. McParland, S. M. Kedziora, G. J. Zigra, D. S. Valdes, M. Kirchner, O. Popp, S. Geisberger, O. Nonn, T. V. Karlsen, G. N'Diaye, A. Yarritu, H. Bartolomaeus, T. U. Bartolomaeus, , D. N. Mueller

The paper develops methods to collect intestinal interstitial fluid from different segments and shows segment-specific differences in microbiota-derived metabolites, cytokines, and proteins compared to plasma and serum.

Cardiovascular Research · Jan 10, 2025Peer-reviewedMicrobiology

Cellular hnRNPA0 limits HIV-1 production by interference with LTR-activity and programmed ribosomal frame-shifting

F. Roesmann, H. Sertznig, K. Klaassen, A. Wilhelm, D. Heininger, C. Elsner, M. L. Santiago, S. Esser, K. Sutter, U. Dittmer, M. Widera

This study shows hnRNPA0 limits HIV-1 replication by inhibiting LTR activity and ribosomal frameshifting, with lower expression in HIV-infected individuals.

bioRxiv · Aug 8, 2023 · PreprintMicrobiology

Generation of a Sleeping Beauty transposon-based cellular system for rapid and sensitive identification of SARS-CoV-2 host dependency and restriction factors

M. Widera, A. Wilhelm, T. Toptan, J. M. Raffel, E. Kowarz, F. Roesmann, A. L. Siemund, V. Luciano, M. Kuelp, J. Reis, S. Bracharz, C. Pallas, S. Ciesek, R. Marschalek

This paper develops a Sleeping Beauty transposon-based cell system for rapid and sensitive detection of SARS-CoV-2 infection and screening of host factors.

bioRxiv · Apr 27, 2021 · PreprintMicrobiology

Fast, efficient and virus-free generation of TRAC-replaced CAR T cells

J. Kath, W. Du, B. Thommandru, R. Turk, L. Amini, M. Stein, T. Zittel, S. Martini, L. Ostendorf, A. Wilhelm, L. Akyuez, A. Rehm, U. E. Hoepken, A. Pruss, A. Kuenkele, , D. L. Wagner

This paper presents a virus-free method to generate CAR T cells by inserting CARs into the TRAC locus using CRISPR-Cas and HDR, achieving up to 68% TCR-to-CAR replacement.

bioRxiv · Feb 14, 2021Immunology