Author

B. Prusty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Approach:statistical model· 4 Research Focus:gene regulatory network inference· 3 Approach:deep learning· 2 Organism:human· 2 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

F. Erhard· 4 shared T. Hennig· 3 shared A. J. Rutkowski· 2 shared A. L'Hernault· 2 shared A. W. Whisnant· 2 shared C. C. Friedel· 2 shared L. Doelken· 2 shared L. Dölken· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersMicrobiology

F. Erhard

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4 papers

Recent·Most cited

Decoding murine cytomegalovirus

M. Lodha, I. Muchsin, C. Jürges, V. Juranic Lisnic, A. L'Hernault, A. Rutkowski, B. Prusty, A. Grothey, A. Milic, T. Hennig, S. Jonjic, C. Friedel, F. Erhard, L. Doelken

This paper reannotates MCMV gene expression using multi-omics data, identifying hundreds of novel transcripts and ORFs, including small ORFs that regulate gene expression and a new immediate-early transcript.

bioRxiv · Nov 10, 2022 · PreprintMicrobiology

Multi-omics reveals principles of gene regulation and pervasive non-productive transcription in the human cytomegalovirus genome

C. S. Jürges, M. Lodha, V. T. K. Le-Trilling, P. Bhandare, E. Wolf, A. Zimmermann, M. Trilling, B. Prusty, L. Dölken, F. Erhard

The paper uses multi-omics data to model HCMV gene regulation, identifying over 2,600 viral transcripts and explaining protein expression kinetics through transcription start sites and RNA stability.

bioRxiv · Jan 7, 2022 · PreprintMicrobiology

Dissecting HSV-1-induced host shut-off at RNA level

C. C. Friedel, A. W. Whisnant, L. Djakovic, A. J. Rutkowski, M.-S. Friedl, M. Kluge, J. C. Williamson, S. Sai, R. O. Vidal, S. Sauer, T. Hennig, B. Prusty, P. J. Lehner, N. J. Matheson, F. Erhard, L. Dölken

This study quantifies HSV-1-induced host shut-off mechanisms and identifies gene-specific transcriptional changes during early infection.

bioRxiv · May 20, 2020 · PreprintMicrobiology

Integrative functional genomics decodes herpes simplex virus 1

A. W. Whisnant, C. S. Juerges, T. Hennig, E. Wyler, B. Prusty, A. J. Rutkowski, A. L'Hernault, M. Goebel, K. Doering, J. Menegatti, R. Antrobus, N. J. Matheson, F. W. Kuenzig, G. Mastrobuoni, C. Bielow, , L. Doelken

This study decodes the complete HSV-1 transcriptome and translatome during lytic infection, identifying novel transcripts, ORFs, and regulatory elements.

bioRxiv · Apr 9, 2019Microbiology