Author

M. Lodha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. Prusty· 2 shared F. Erhard· 2 shared A. Fassati· 1 shared A. Grothey· 1 shared A. L'Hernault· 1 shared A. Milic· 1 shared A. Rutkowski· 1 shared A. Zhyvoloup· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

B. Prusty

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Author profile →

3 papers

Recent·Most cited

Decoding murine cytomegalovirus

M. Lodha, I. Muchsin, C. Jürges, V. Juranic Lisnic, A. L'Hernault, A. Rutkowski, B. Prusty, A. Grothey, A. Milic, T. Hennig, S. Jonjic, C. Friedel, F. Erhard, L. Doelken

This paper reannotates MCMV gene expression using multi-omics data, identifying hundreds of novel transcripts and ORFs, including small ORFs that regulate gene expression and a new immediate-early transcript.

bioRxiv · Nov 10, 2022 · PreprintMicrobiology

Multi-omics reveals principles of gene regulation and pervasive non-productive transcription in the human cytomegalovirus genome

C. S. Jürges, M. Lodha, V. T. K. Le-Trilling, P. Bhandare, E. Wolf, A. Zimmermann, M. Trilling, B. Prusty, L. Dölken, F. Erhard

The paper uses multi-omics data to model HCMV gene regulation, identifying over 2,600 viral transcripts and explaining protein expression kinetics through transcription start sites and RNA stability.

bioRxiv · Jan 7, 2022 · PreprintMicrobiology

Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth

T. R. Wiche Salinas, Y. Zhang, D. Sarnello, A. Zhyvoloup, L. Raymond-Marchand, D. Planas, M. Lodha, D. Chatterjee, K. Karwacz, S. Oxenford, J.-P. Routy, H. Amrine-Madsen, P. Ancuta, A. Fassati

This paper identifies RORC2 as a key host factor that promotes HIV-1 gene expression and viral outgrowth in Th17 cells, suggesting it as a new therapeutic target.

bioRxiv · Mar 27, 2021Microbiology