The meninges host a unique compartment of regulatory T cells that bulwarks adult hippocampal neurogenesis
M. Marin-Rodero, E. Cintado, A. J. Walker, T. Jayewickreme, F. A. de Pinho-Ribeiro, Q. Richardson, R. Jackson, I. Chiu, C. Benoist, J. L. Trejo, b. stevens, D. Mathis
The paper identifies a unique population of regulatory T cells in the murine meninges that maintain brain homeostasis by suppressing interferon-gamma-producing lymphocytes and preventing hippocampal damage.
bioRxiv · Jun 17, 2024Immunology