Fortuitous Somatic Mutations during Antibody Evolution Endow Broad Neutralization against SARS-CoV-2 Omicron Variants
J. Wu, Z. Chen, Y. Gao, Z. Wang, J. Wang, B.-Y. Chiang, Y. Zhou, Y. Han, W. Zhan, M. Xie, W. Jiang, X. Zhang, A. Hao, A. Xia, J. He, , Q. Wang
The paper identifies an antibody with broad neutralization against SARS-CoV-2 Omicron variants and shows how somatic mutations enhance its neutralization breadth and potency.
Cell Reports · May 1, 2023Peer-reviewedImmunology