Author

C. De

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

C. K. Chu· 2 shared D. Liu· 2 shared J. F. Moffat· 2 shared U. S. Singh· 2 shared A. Pertsinidis· 1 shared C. Hartline· 1 shared D. Depledge· 1 shared J. Breuer· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

C. K. Chu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mechanisms of transcription control by distal enhancers from high-resolution single-gene imaging

L. Cheng, C. De, J. Li, A. Pertsinidis

This study uses single-gene imaging to investigate how distal enhancers control promoters over long distances, revealing that enhancer-promoter interactions occur at 200 nm and involve transcription factor clusters that increase transcriptional bursting frequency.

bioRxiv · Mar 19, 2023 · PreprintBiophysics

Repression of MUC1 promotes expansion and suppressive function of myeloid-derived suppressor cells in pancreatic ductal adenocarcinoma and breast cancer murine models.

M. Sahraei, L. Das Roy, M. Bose, C. De, S. Nath, P. Mukherjee

This study shows that MUC1 repression in MDSCs enhances their proliferation and suppressive function in pancreatic and breast cancer models, leading to increased tumor growth and immune suppression.

bioRxiv · Dec 7, 2020Cancer Biology

β-L-1- Uracil (L-BHDU) Inhibits Varicella Zoster Virus Replication by Depleting the Cellular dTTP Pool

C. De, D. Liu, U. S. Singh, C. K. Chu, J. F. Moffat

This study shows L-BHDU inhibits VZV replication by depleting dTTP, suggesting it targets viral DNA synthesis rather than cellular metabolism.

bioRxiv · Feb 13, 2020 · PreprintMicrobiology

β-L-1- uracil (L-BHDU) effectiveness against varicella-zoster virus and herpes simplex virus type 1 depends on thymidine kinase activity

C. De, D. Liu, D. Depledge, J. Breuer, U. S. Singh, C. Hartline, M. Prichard, C. K. Chu, J. F. Moffat

This study shows L-BHDU's effectiveness against VZV and HSV-1 relies on thymidine kinase activity, as resistant strains have mutations in TK that impair drug phosphorylation.

bioRxiv · Feb 13, 2020 · PreprintMicrobiology